Insights into Putative Health Implications of Gelam (Melaleuca cajuputi) Honey: Evidence from In-Vivo and In-Vitro Studies
نویسندگان
چکیده
Honey has been used as a therapeutic agent since ancient times for health maintenance and the treatment of various ailments. In modern days, researchers reappraised the therapeutic values of honey, such as anti-oxidative, anti-inflammatory, antimicrobial, anti-diabetic, anti-tumor, and wound healing properties. These findings supported its applications in the modern healthcare system as complementary medicine. Gelam honey (GH) is a monofloral Malaysian honey which has been proven to have considerable health benefits. This paper presents a state of the art review on the therapeutic values of GH. A descriptive elucidation is performed to elaborate a wide spectrum of biological activities of GH using evidence from a considerable body of literature. The compositional and physiochemical characteristics of GH have contributed substantially to its putative biological properties. A brief explanation will be presented on GH attributes to familiarize readers with this novel natural health product.
منابع مشابه
In-vitro screening of Malaysian honey from different floral sources for antibacterial activity on human pathogenic bacteria.
BACKGROUND Different researches on therapeutic effects of honey have been conducted in different regions; however the study on the potential antibacterial activity of Malaysian honey is still limited. In this study, antibacterial activities of different monofloral honey samples were tested against several common human pathogenic bacteria. MATERIALS AND METHODS The well-diffusion method, minim...
متن کاملAntifilarial and Antibiotic Activities of Methanolic Extracts of Melaleuca cajuputi Flowers
We evaluated the activity of methanolic extracts of Melaleuca cajuputi flowers against the filarial worm Brugia pahangi and its bacterial endosymbiont Wolbachia. Anti-Wolbachia activity was measured in worms and in Aedes albopictus Aa23 cells by PCR, electron microscopy, and other biological assays. In particular, microfilarial release, worm motility, and viability were determined. M. cajuputi ...
متن کاملGelam Honey Scavenges Peroxynitrite During the Immune Response
Monocytes and macrophages are part of the first-line defense against bacterial, fungal, and viral infections during host immune responses; they express high levels of proinflammatory cytokines and cytotoxic molecules, including nitric oxide, reactive oxygen species, and their reaction product peroxynitrite. Peroxynitrite is a short-lived oxidant and a potent inducer of cell death. Honey, in add...
متن کاملA Brief Review about the Effect of Honey on Diabetic Foot Ulcer; from In Vitro Studies to Clinical Trials
Diabetes mellitus has many complications; one of the most important ones is diabetic foot ulcer (DFU). Due to the increasing prevalence of diabetes in the world and evidences of the role of honey in treatment of DFU, we decided to review the effect of honey on DFU. We searched the keywords of “honey”, “diabetic foot ulcer”, “treatment”, “diabetes mellitus”, “wound dressing” and “wound healing” ...
متن کاملThe Efficacy of Gelam Honey Dressing towards Excisional Wound Healing
Honey is one of the oldest substances used in wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group, Intrasite Gel group, and Gelam honey group) with 2 cm by 2 cm full thickness, excisional wound created on neck area. Wounds were dressed topically according...
متن کامل